Table 2 miRNA expression profiles in endometriosis

miR-424

Human

PI3K/AKT

Induced cell proliferation and angiogenesis

[52, 61]

miR-9; miR-21

Human

BCL2; BCL2L11; PTEN; PDCD4

Anti-apoptosis; tumor suppressors

miR-200b

Human

ZEB1; ZEB2

Increased cell invasion and migration

[51, 53, 62]

miR-145

Human

-

Promotes apoptosis and inhibits cancer cell invasion and metastasis

miR-196B

Human

HOXA9; HOXA10

Angiogenesis

miR-135a

Human

HOXA10

Suppressed genes for implantation

[56]

miR-34

Human

KRAS; BCL6

Suppressed tumor growth

[58]

miRNA let-7

Human

KRAS

Cell differentiation and inhibit cellular reprogramming;

[11, 57]

miR-125b

Human

BMPR1B

Control apoptosis and cellproliferation;

[63, 64]

miR-145

Human

VEGFA; EGFR2; PTEN; CXCR4

Inhibit cell proliferation and invasiveness

[65]

miR-200

Human

ZEB1; ZEB2

Maintain epithelial status

[54, 66]

miRNA let-7

Human

KRAS; CYP19A1

Suppressed tumor growth

[59]

miR-451

Mouse

WnT/WNT

Pre-implantation embryogenesis

[67]

miR-15b; miR-16

Human

VEGF-A; COX-2

Pro-angiogenic

[68]

miR-141; miR-200c

Human

TGF-beta; ZBI

Promotes invasion of cancer cells

[69]

miR-15b; miR-16

Human

BCL2

Anti-apoptotic protein

[70]

miR-126

Human

VEGF; FGF

Neovascularization

[71]

miR-126

Human

EGFL7

Induce migration of endothelial cell during neovascularization

[72]

miR-199

Murine

COX-2

Affected to implantation

[73]

miR-20a

Mouse

CCND1

Epithelial cell proliferation

[74]

miR-196b

Human

BCL-2

Cell Proliferation and anti-apoptotic

[75]

miR-503

Human

Cyclin D1; VEGF-A; BCL-2

Proliferation and anti-apoptotic, neovascularization, extracellular matrix contractility

[76]