Table 2 Comparison of stimulation and cycle outcomes in the two study groups
Variables | Letrozole group (N = 34) | Control group (N = 30) | P value |
|---|---|---|---|
Total gonadotropins ampoules (75 IU) | \(28.4 \pm 8.5\) | \(34.3 \pm 12.6\) | 0.03 |
Duration of stimulation (day) | \(10.8 \pm 1.9\) | \(11.2 \pm 2.5\) | 0.58 |
Estradiol level on trigger day (pg/ml) | \(1837.5 \pm 577.6\) | \(2283.7 \pm 606.4\) | 0.004 |
No. of follicles with 14–17 mm in diameter at trigger | \(2.4 \pm 2.1\) | \(2.8 \pm 2.3\) | 0.48 |
No. of follicles > 17 mm in diameter at trigger | \(2.7 \pm 1.2\) | \(2.2 \pm 0.74\) | 0.11 |
No. of retrieved oocytes | \(11.5 \pm 8.9\) | \(8.2 \pm 7.7\) | 0.12 |
No. of metaphase II oocytes | \(8.4 \pm 7.1\) | \(6.5 \pm 6.3\) | 0.29 |
No. of obtained embryos | \(4.4 \pm 2.6\) | \(4.0 \pm 3.4\) | 0.63 |
No. of top-quality embryo | 3.1 ± 2.3 | 2.8 ± 2.8 | 0.62 |
No. of cryopreserved embryos | \(4.0 \pm 3.0\) | \(3.6 \pm 3.7\) | 0.61 |
No. of all freeze cases, n (%) | 30 (88.2) | 28 (93.3) | 0.84 |
No. of cases with fresh embryos transferred, n (%) | 4 (11.8) | 2 (6.7) | 0.80 |
Chemical pregnancy rate/total ET (%) | 12/ 24 (50) | 3/21 (14.3) | 0.01 |
Clinical pregnancy/total ETa (%) | 10/24 (41.6) | 3/21 (14.3) | 0.04 |
Miscarriage rate/total ET (%) | 2/24 (8.3) | 0/0 | 0.39 |
Live birth rate/total ET | 8/24 (33.8) | 3/21 (14.3) | 0.12 |