Table 1 Immunohistochemical localization of signaling components of mTOR pathway

mTOR

 SE

7.88 ± 3.68

7.50 ± 3.31

 GE

7.38 ± 3.16

8.83 ± 3.46

 Stroma

5.06 ± 0.78

4.77 ± 2.48

p-mTOR

 SE

6.56 ± 1.92

9.07 ± 3.24

 GE

8.13 ± 2.60

11.10 ± 3.35*

 Stroma

4.38 ± 1.06

7.60 ± 2.35**

p-mTOR/mTOR

 SE

0.98 ± 0.41

1.28 ± 0.37

 GE

1.24 ± 0.42

1.36 ± 0.48

 Stroma

0.88 ± 0.19

1.86 ± 0.74**

TSC1 (Hamartin)

 SE

11.25 ± 3.67

5.33 ± 4.42

8.06 ± 4.37

3.67 ± 3.61

 GE

9.54 ± 5.01

7.00 ± 5.40

8.78 ± 3.88

6.47 ± 4.97

 Stroma

7.83 ± 3.43

6.39 ± 4.35

5.15 ± 3.45*

5.50 ± 3.59

TSC2 (Tuberin)

 SE

11.12 ± 4.20

7.75 ± 4.44

 GE

12.13 ± 2.61

8.86 ± 4.33*

 Stroma

6.96 ± 4.03

4.00 ± 1.37*

p-Tuberin

 SE

11.00 ± 2.98

5.85 ± 3.87

11.90 ± 4.43

7.55 ± 2.11

 GE

10.15 ± 2.40

7.65 ± 1.41

11.12 ± 3.25

10.19 ± 3.85

 Stroma

4.70 ± 2.10

7.25 ± 1.75

8.58 ± 3.13**

10.08 ± 4.15

p-Tuberin/Tuberin

 SE

1.018 ± 0.382

1.58 ± 1.30

 GE

0.83 ± 0.27

1.63 ± 0.90*

 Stroma

0.84 ± 0.50

2.36 ± 1.06***

p-S6

 SE

9.96 ± 4.98

5.62 ± 5.48

9.33 ± 4.13

3.17 ± 4.23

 GE

6.50 ± 3.25

5.04 ± 4.94

9.50 ± 3.86*

4.56 ± 4.26

 Stroma

5.04 ± 2.55

4.17 ± 3.31

7.83 ± 3.22*

4.75 ± 2.92

Ki67

 SE

3.00 ± 3.64

4.96 ± 3.78

 GE

3.29 ± 3.46

23.38 ± 21.19***

 Stroma

13.41 ± 10.37

36.67 ± 27.06**