Table 1 Summary of the articles included in the review
Article | Type of article | Sample size | Groups assessed | Incidence of HPV infection | HPV effect on semen analysis | Reproductive outcomes |
|---|---|---|---|---|---|---|
Foresta et al. (2010) [7] | Cross-sectional | 290 | General population, high-risk male population, and infertile patients | 2.2% in the general population 10.2% in the infertile population | Reduced motility | Not available |
Schillaci et al. (2013) [13] | Cross-sectional | 308 | Patients undergoing IVF treatment | 7.8% in the general population | No significant impairment noted | Not available |
Hebnes et al. (2014) [14] | Meta-analysis | 8291/31 | General and high-risk male population | 12.4% in the general population 30.9% in the high-risk population | Not available | Not available |
Laprise et al. (2014) [15] | Meta-analysis | 4029/18 | General population and fertility clinic attendees | 10% in the general population 16% in clinic attendees | Not available | Not available |
Garolla et al. (2016) [18] | Cross-sectional | 226 | Patients undergoing IUI/IVF treatment | 23.9% in the infertile population | No significant impairment noted | Decreased pregnancy rate Increased miscarriage rate |
Luttmer et al. (2016) [16] | Cross-sectional | 430 | Fertility clinic attendees | 14.9% in the infertile population | No significant impairment noted | Not available |
Damke et al. (2017) [19] | Cross-sectional | 229 | Fertility clinic attendees | 16.6% in the infertile population | Hypospermia, abnormal seminal viscosity, higher mean pH, and higher mean numbers of leukocytes | Not available |
Lyu et al. (2017) [12] | Meta-analysis | 5194/31 | General population and fertility clinic attendees | 11.4% in the general population 20.4% in clinic attendees | Not available | Increased risk of infertility |
Xiong et al. (2018) [20] | Meta-analysis | 1955/8 | Infertile males | Not available | Not available | Increased risk of infertility |
Weinberg et al. (2020) [21] | Meta-analysis | 2750/16 | Patients undergoing IVF treatment | Not available | Motility significantly affected | Decreased pregnancy rate Increased miscarriage rate |