The effect of exercise on anti-Mullerian hormone levels in patients with polycystic ovary syndrome: a systematic review and meta-analysis

Middle East Fertility Society Journal

Table 5 GRADE evidence profile of exercise vs. no exercise in women with PCOS on reduction of AMH level

Certainty assessment							No. of patients		Effect		Certainty	Importance
No. of studies	Study design	Risk of bias	Inconsistency	Indirectness	Imprecision	Other considerations	Exercise	No. of exercise	Relative (95% CI)	Absolute (95% CI)	Certainty	Importance
Anti Mullerian hormone (follow-up: mean 12.33 weeks)
6	Randomized trials	Very serious^a	Very serious^b	Not serious	Serious^c	None	139	134	-	SMD 0.66 SD more (0.06 more to 1.26 more)	⨁◯◯◯ Very low	Critical

CI confidence interval, SMD standardized mean difference
^athere was a high risk of bias regarding study design and incomplete reporting. Random sequence generation, allocation concealment, and binding in most the studies are not mentioned or are unclear
^bdowngraded two level because I² was more than 80%
^cdowngraded one level because of imprecision; the total number of the participants is < 400