Author, year (reference) | Place of study | Age (year) Intervention group | Sample size | BMI (kg/m2) | Mean ± SD of intervention group (ng/ml) | Mean ± SD of control group (ng/ml) | Type of intervention | Type of study | Diagnostic tool | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Control group | Intervention group | Before | After | Before | After | p-value | Before | After | p-value | ||||||
Saremi and Yaghoubi 2016 [21] | Iran | 28.31 ± 5.3 (18–50) | 10 | 10 | 24.88 ± 1.23 | 25.26 ± 1.37 | 14.4 ± 5.2 | 14.1 ± 5.5 | ˃ 0.05 | 11.22 ± 4.1 | 11.6 ± 3.9 | ˃ 0.05 | 8 weeks of resistance training in three sessions per week (each training session includes 1 to 2 rounds of 5 to 20 repetitions with an intensity of 40 to 60% of a maximum repetition) | Semi-experimental with pre-test-post-test design | ELISA |
Saremi et al., 2013 [22] | Iran | 30.24 ± 4.41 (20–40) | 11 | 11 | 28.29 ± 5.73 | 28.48 ± 6.29 | 14.44 ± 7.62 | 15.93 ± 7.74 | 0.2 | 16.44 ± 5.47 | 17.20 ± 6.44 | - | 8 weeks of aerobic exercise three sessions per week (40–45 min per session) | Semi-experimental with pre-test-post-test design and control group | ELISA |
Saremi and Rajabi 2016 [23] | Iran | 28.16 ± 4.29 (20–40) | 10 | 10 | 32.42 ± 4.65 | 25.26 ± 1.37 | 12.3 ± 4.1 | 12.1 ± 4.5 | ˃ 0.05 | 10.36 ± 4.4 | 10.4 ± 3.7 | ˃ 0.05 | 8 weeks of aerobic exercise three sessions per week (50–60 min per session) | Semi-experimental with pre-test-post-test design | ELISA |
Saremi et al., 2014 [24] | Iran | 28.16 ± 4.29 (20–40) | 10 | 10 | 30.01 ± 4.7 | 29.08 ± 4.6 | 10.11 ± 3.8 | 7.6 ± 3.6 | ˂ 0.05 | 15.1 ± 3.5 | 17.2 ± 2.8 | - | 8 weeks of pilates training three times a week (60 min per session) | Semi-experimental with pre-test-post-test design and control group | ELISA |
Al-Eisa et al., 2017 [25] | Egypt | 27.9 ± 4.1 | 30 | 30 | 33.45 ± 2.75 | 28.5 ± 2.25 | 10.5 ± 3.56 | 8.92 ± 3.23 | ˂ 0.05 | 9.5 ± 5.45 | 7.9 ± 4.25 | - | 12 weeks of aerobic exercise | Semi-experimental with pre-test-post-test design | ELISA |
Vosnakis-1, 2013 [26] | Greece | 26.95 ± 4.77 | 20 | 61 | 34.83 ± 6.39 | 31.9 ± 6.09 | 7.07 ± 4.86 | 10.87 ± 5.84 | 0.003 | 5.34 ± 1.84 | 5.00 ± 2.55 | 0.596 | 12 weeks of aerobic exercise | Semi-experimental with pre-test-post-test design | ELISA |
Vosnakis-2, 2013 [26] | Greece | 26.95 ± 4.77 | 20 | 61 | 34.83 ± 6.39 | 30.21 ± 5.78 | 7.07 ± 4.86 | 8.26 ± 4.91 | 0.005 | 5.34 ± 1.84 | 5.16 ± 3.11 | 0.963 | 24 weeks of aerobic exercise | Semi-experimental with pre-test-post-test design | ELISA |
Hosseini et al., 2019 [27] | Iran | 30.01 ± 1.70 (20–35) | 20 | 20 | 27.01 ± 1.15 | 26.54±1.03 | 10.67 ± 0.75 | 10.4 0± 0.77 | 0.001 | 12.65 ± 1.23 | 12.41 ± 0.94 | 0.16 | 8 weeks of resistance exercise | Randomized clinical trial (registration: not reported) | ELISA |
Nybacka Nybacka et al., 2013 [28] | Sweden | 31.3 ± 4.8 | 14 | 17 | 34.8 ± 5.2 | 34.1 ± 5.7 | 6.6 ± 3.9 | 6.6 ± 4.2 | - | 7.1 ± 4.3 | 6.1 ± 4.0 | - | 16 weeks three times a week resistance exercise | Randomized clinical trial (registration: ISRCTN48342048) | ELISA |
Wu et al., 2021 [29] | China | 32.7 ± 3.2 | 19 | 19 | 23.8 ± 3.0 | 21.3 ± 2.1 | 17.6 ± 5.1 | 14.8 ± 3.6 | 0.021 | 18.4 ± 5.8 | 17.9 ± 4.7 | 0.684 | 12 weeks of aerobic exercise | Randomized clinical trial (registration: not reported) | ELISA |
Moran et al., 2011 [30] | Australia | 30.6 ± 7.1 | 7 | 8 | 33.1 ± 3.6 | 32.9 ± 4.0 | 5.91 ± 2.05 | 4.59 ± 1.53 | 0.007 | 5.85 ± 2.3 | 5.0 ± 2.1 | - | 12 weeks of resistance exercise 3 times a week and 1-h session | Randomized clinical trial (registration: ISRCTN84763265) | - |
Leonhardt et al., 2015 [31] | Sweden | 29.5 (21–37) | 29 | 30 | 26.6 (20.4–44.3) | 24.5 (20.6–37.6) | 6.70 ± 2.26 | 3.98 ± 1.56 | - | 6.60 ± 2.3 | 8.28 ± 2.5 | - | 16 weeks of resistance exercise 3 times a week and 1-h session | Randomized clinical trial (registration: ClinicalTrials.gov (identifier NCT00484705)) | ELISA |
Nidhi et al., 2013 [32] | India | 16.22 ± 1.13 | 45 | 45 | 20.39 ± 2.00 | 20.41 ± 2.07 | 6.25 ± 3.79 | 3.73 ± 2.25 | 0.006 | 6.45 ± 3.91 | 5.57 ± 2.79 | - | 12 weeks, yoga exercises in a 1-h session once a day | Randomized clinical trial (registration: REFCTRI-2008 000291) | - |