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Table 1 Effects of treatment with zinc sulfate and N-acetylcysteine on fecundity in phthalate-treated male Wistar rats

From: Toxicological outcome of phthalate exposure on male fertility: Ameliorative impacts of the co-administration of N-acetylcysteine and zinc sulfate in rats

Group (n = 6)

%Pregnancy

Gestation length (days)

Average litter size

Average pup weight (g)

Pop survival rate after 1 month (%)

Control

100

22±0.58

7.0±0.58

10.2±0.35

79

PHT

33.3*

20±0.00

4.0±0.00*

9.9±0.00

100

PHT+ ZnSO4

66.7

24±1.00

6.5±0.50

10.1±0.30

77

PHT+NAC

100a

23±1.53

6.0±0.33

9.87±0.17

79

PHT+ ZnSO4+NAC

100a

24.5±1.00

8.0±0.58a

9.63±0.09

77

  1. PHT phthalate, ZnSO4 zinc sulfate, NAC N-acetylcysteine
  2. *,ap < 0.05 was considered statistically significant when compared with the control and PHT-treated groups respectively