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Table 1 Studies for poor ovarian reserve

From: Intraovarian platelet-rich plasma: current status

Study

Type of study

Number of patients

Outcome

Sills et al. 2019, [6]

Case series

4

Improved ovarian function in all cases, Increase AMH, Decrease FSH or both. IVF: retrieval of 5.3 ± 1.3 MII oocytes.

Petryk et al. 2020 [8]

Interventional

38

Significant improvement in hormone levels; 6 babies were born, 10 pregnancies were achieved, and 4 out of the 10 were from natural conception.

Singh et al. 2020 [9]

Interventional

30

No benefit in increasing AMH, AFC, ovarian response to COS or IVF outcome

Mello et al. 2020 [10]

Controlled non randomized

46

PRP Vs control G: Sig improvement in FSH, AMH, AFC. Biochemical (26.1% vs 5.4%) and cl pregnancy (23.9% vs 5.4%) were higher.

Sills et al. 2020 [11]

Case series

182

Improved AMH in (28%) with median increase of 167%. Mean interval to maximum AMH increase was 4 w (range 2–10 w).

Jacman et al. 2020 [12]

Case series retrospective

140

PRP can stimulate follicular development for at least 6 weeks following the intraovarian injection.

Total

 

369

Â