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Table 6 Semen parameters according to the various genotypes of rs8177404 and rs3828599 polymorphisms in fertile (n=100) and infertile group (n=100)

From: Glutathione peroxidase 3 (extracellular isoform) levels and functional polymorphisms in fertile and infertile men

Genotypes

Sperm motility1 (%)

Sperm concentration (million/ml)

Sperm normal morphology (%)

Progressively motile sperm

Non-progressively motile sperm

Immotile sperm

GPX3, rs8177404

Fertile group

  TT (n=77)

35.44±8.03

35.95±5.35

30.83±6.42

64.23±10.13

18.78±6.90

  TC (n=16)

31.31±7.28

34.76±7.27

36.93±8.55a

59.14±9.12

16.78±9.23

  CC (n=7)

23.17±9.34a,b

32.52±6.10

44.21±4.71a,b

56.77±11.10

13.28±5.82a

Infertile group

  TT (n=59)

15.16±5.21

31.14±8.92

53.43±16.71

40.14±12.11

6.14±3.01

  TC (n=28)

11.10±8.63a

28.03±9.04

59.18±11.29

35.46±12.08

5.08±4.26

  CC (n=13)

8.72±5.12a

27.73±8.19

62.19±7.38

30.16±10.61a

4.37±2.84

GPX3, rs3828599

Fertile group

  AA (n=45)

27.01±9.82

29.94±10.73

39.03±10.76

57.25±17.43

16.89±10.20

  AG (n=31)

29.38±8.06

32.02±8.67

38.37±12.72

58.92±15.40

19.01±7.83

  GG (n=24)

31.49±6.27a

30.93±10.53

37.82±13.01

64.18±12.52

18.07±8.81

Infertile group

  AA (n=61)

13.79±8.30

29.10±11.42

57.23±10.63

38.01±14.12

5.43±2.91

  AG (n=28)

16.01±6.05

31.88±7.91

52.71±17.87

37.74±15.04

4.62±3.91

  GG (n=11)

17.38±6.71

32.07±7.20

49.82±13.63a

41.27±11.92

5.05±3.66

  1. Results are presented as mean ± SD
  2. 1Grade of sperm movement according to WHO [2010] criteria
  3. Significant difference in comparison with awild type and bheterozygous variant