Fig. 3From: Ovarian odorant-like biomolecules in promoting chemotaxis behavior of spermatozoa olfactory receptors during migration, maturation, and fertilizationA diagram showing the role of various stimuli from the female reproductive tract in sperm hyperactivation. Activation of CatSper (Ca2+ channel) by different stimuli mediates intracellular calcium influx into the flagellum resulting and stimulate flagellar beating thereby enabling penetration into the viscous mucus. Also, there is a subsequent release of stored Ca2+ at the midpiece region of the spermatozoa following CatSper-mediated Ca2+ influx thereafter promoting hyperactivated motilityBack to article page