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Fig. 3 | Middle East Fertility Society Journal

Fig. 3

From: Ovarian odorant-like biomolecules in promoting chemotaxis behavior of spermatozoa olfactory receptors during migration, maturation, and fertilization

Fig. 3

A diagram showing the role of various stimuli from the female reproductive tract in sperm hyperactivation. Activation of CatSper (Ca2+ channel) by different stimuli mediates intracellular calcium influx into the flagellum resulting and stimulate flagellar beating thereby enabling penetration into the viscous mucus. Also, there is a subsequent release of stored Ca2+ at the midpiece region of the spermatozoa following CatSper-mediated Ca2+ influx thereafter promoting hyperactivated motility

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