Relation of serum vitamin D level in polycystic ovarian syndrome (PCOS) patients to ICSI outcome

Middle East Fertility Society Journal

Table 4 Correlations between serum 25 (OH) vitamin D and the number of retrieved and fertilized oocytes, and other ICSI cycle outcomes

Variables	Correlation coefficient (95% CI)	P value
Vitamin D vs number of retrieved oocytes	r = 0.35 (0.15, 0.53)^a	0.001*
Vitamin D vs number of retrieved oocytes	0.47 (0.1, 0.9)^b	0.018*
Vitamin D vs number of fertilized oocytes	r = 0.33 (0.03, 0.57)^a	0.03*
Vitamin D vs number of fertilized oocytes	0.3 (0.02, 0.58)^b	0.03*
Vitamin D vs number of implanted embryos	− 0.032 (− 0.26 to 0.12)^a	0.7
Vitamin D vs number of implanted embryos	0.01 (− 0.017, 0.03)^b	0.57
Vitamin D vs number of grade 1 embryos	0.01 (− 0.22 to 0.24)^a	0.9
Vitamin D vs number of grade 1 embryos	0.01 (− 0.015, 0.03)^b	0.5
Variables	Odds ratio (95% CI)	P value
Vitamin D vs chemical pregnancy	1.01 (0.9, 1.09)^c	0.3
Vitamin D vs clinical pregnancy	1.04 (0.95, 1.14)^c	0.4

^aPearson correlation coefficient
^bCoefficient in multivariable regression analysis adjusting for possible confounders, namely, age, BMI, and type of ovulation-triggering agent (HCG vs GnRH agonist)
^cLogistic regression for clinical and chemical pregnancy as response variables vs serum 25 (OH) D vitamin level as the independent variables with inclusions of the following confounders in the model: age, BMI, type and duration of infertility, previous IVF failure, and the type of triggering agent
*Statistical significance