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Table 9 Effect of BMP15 genotypes on some physiological parameters of Type 2 diabetic patients among duration of disease

From: Association between polymorphism in BMP15 and GDF9 genes and impairing female fecundity in diabetes type 2

Indices

Diabetes groups (LSM ± SE)

P value

AC

AA

0–5

> 5–10

> 10

0–5

> 5–10

> 10

BMI (kg/m2)

30.55 ± 0.95a

28.07 ± 1.11b

30.76 ± 1.66a

32.96 ± 1.01a

30.77 ± 1.18b

29.94 ± 1.78b

0.02**

Waist circumference (cm)

101.87 ± 2.20a

104.00 ± 2.01a

103.12 ± 4.25a

106.00 ± 2.35a

97.85 ± 2.15a

99.85 ± 4.54a

0.33

FBG (mmol/l)

12.76 ± 1.52a

12.17 ± 1.02a

14.27 ± 1.22a

9.64 ± 1.63a

11.71 ± 1.09a

11.90 ± 1.30a

0.31

HbA1c (%)

7.55 ± 0.50a

7.97 ± 0.51b

8.11 ± 0.70b

6.15 ± 0.54a

7.12 ± 0.54b

7.62 ± 0.75b

0.04**

FSH (mIU/ml)

26.22 ± 3.19a

30.12 ± 3.88a

28.82 ± 2.08a

32.50 ± 5.69a

29.29 ± 3.56a

34.05 ± 4.78a

0.97

LH (mIU/ml)

11.84 ± 1.65a

19.99 ± 4.23b

17.18 ± 2.06b

9.51 ± 1.77a

12.64 ± 4.52b

13.73 ± 2.21b

0.02**

Estradiol (pg/ml)

20.89 ± 0.60a

21.83 ± 0.40a

21.66 ± 0.47a

20.88 ± 0.65a

22.37 ± 0.77a

21.68 ± 0.50a

0.35

  1. BMI body mass index, FBG fasting blood glucose, HbA1c glycolytic hemoglobin, FSH follicle stimulating hormone, LH luteinizing hormone
  2. Least square means ± standard error, *P < 0.05, **P < 0.01
  3. a,bSignificant differences in means represent by different letters in the same raw