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Table 3 The impact of weight loss on clinical and phenotype characteristics of obese PCOS group

From: Impact of weight loss on plasma ghrelin level, clinical, and metabolic features of obese women with or without polycystic ovary syndrome

VariablesObese PCOS group (n = 50)
 Base lineWeek 12P value
Body mass index (kg/m2)36.97 ± 1.2902131.1 ± 6.51˂ 0.001*
Waist/hip ratio1.25 ± 0.251071.08 ± 0.25˂ 0.001*
Systolic blood pressure (mm Hg)130.8 ± 7.51127.89 ± 8.4˂ 0.05*
Diastolic blood pressure (mm Hg)87.25 ± 4.3886.32 ± 4.510.273
Hirsutism score13.93 ± 2.3610.2 ± 4.96˂ 0.001*
Ovarian volume11.92 ± 3.248.84 ± 4.4˂ 0.001*
AFC13.17 ± 3.4810.19 ± 4.83˂ 0.001*
FMI%9.61 ± 0.3358.092 ± 1.69˂ 0.001*
FFMI%27.36 ± 0.9523.03 ± 4.81˂ 0.001*
Total cholesterol (mg/dL)200.03 ± 9.2180.06 ± 26.2˂ 0.001*
Triglycerides (mg/dL)340.8 ± 62.35259.08 ± 93.1˂ 0.001*
LDL cholesterol (mg/dL)146.96 ± 8.8126.9 ± 21.69˂ 0.001*
HDL cholesterol (mg/dL)32.86 ± 2.6536.25 ± 5.48˂ 0.001*
Fasting plasma glucose (mg/dL)94.05 ± 7.0189.6 ± 9.14˂ 0.001*
Fasting serum insulin (lU/mL)13.45 ± 6.728.97 ± 4.61˂ 0.001*
HbA1c (%)5.98 ± 0.0745.87 ± 0.166˂ 0.001*
HOMA-IR3.1 ± 1.552.01 ± 1.15˂ 0.001*
HOMA-β81.9 ± 35.9122.4 ± 71.5˂ 0.001*
FSH (mIU/mL)6.44 ± 1.65.7 ± 1.704˂ 0.05*
LH (mIU/mL)7.6 ± 1.87.01 ± 01.800.059
LH/FSH1.24 ± 0.3781.3 ± 0.4830.457
DHEA-S (mg/mL)1.92 ± 0.6281.36 ± 0.62˂ 0.001*
Total testosterone (ng/mL).85 ± 0.266.68 ± 0.29˂ 0.001*
Androstenedione (ng/mL)1.9 ± 0.4861.56 ± 0.577˂ 0.001*
Dietary characteristics
Energy intake (kcal/day)2384.1 ± 253.81384.1 ± 289.5˂ 0.001*
Meal frequency (meals/day)5.3 ± 1.67.16 ± 0.51˂ 0.001*
Proteins (% TCV/day)26.9 ± 8.0735.9 ± 8.85˂ 0.001*
Lipids (% TCV/day)33.5 ± 10.0516.9 ± 4.28˂ 0.001*
CHO (% TCV/day) l59.8 ± 17.9440.4 ± 5.19˂ 0.001*
  1. *p ˂ 0.05