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Table 2 The impact of weight loss on clinical, anthropometric, and laboratory characteristics of obese non-PCOS group

From: Impact of weight loss on plasma ghrelin level, clinical, and metabolic features of obese women with or without polycystic ovary syndrome

VariablesObese non-PCOS group (n = 60)
 Base lineWeek 12P value
Body mass index (kg/m2)35.87 ± 2.7431.31 ± 5.8˂ 0.001*
Waist/hip ratio1.23 ± 0.261.12 ± 0.274˂ 0.05*
Systolic blood pressure (mm Hg)131.1 ± 6.21129.06 ± 7.70.110
Diastolic blood pressure (mm Hg)86.9 ± 4.2786.5 ± 4.250.589
Hirsutism score6.4 ± 1.456.31 ± 1.640.819
Ovarian volume6.1 ± 2.125.98 ± 2.080.754
AFC6.6 ± 1.7376.2 ± 1.70.439
FMI%9.28 ± 0.858.09 ± 1.56˂ 0.001*
FFMI%26.4 ± 2.4323.05 ± 4.45˂ 0.001*
Total cholesterol (mg/dL)197.9 ± 12.49181.4 ± 24.83˂ 0.001*
Triglycerides (mg/dL)308.8 ± 82.96250.9 ± 91.35˂ 0.001*
LDL cholesterol (mg/dL)139.19 ± 15.9123.5 ± 19.6˂ 0.001*
HDL cholesterol (mg/dL)34.6 ± 4.75137.2 ± 5.681˂ 0.001*
Fasting plasma glucose (mg/dL)93.8 ± 6.7389.51 ± 8.51˂ 0.001*
Fasting serum insulin (lU/mL)16.7 ± 9.53214.5 ± 10.11˂ 0.001*
HbA1c (%)5.9 ± 0.1185.87 ± 0.147˂ 0.001*
HOMA-IR3.9 ± 2.253.29 ± 2.42˂ 0.05*
HOMA-β109.02 ± 70.6132.1 ± 78.50.056
FSH (mIU/mL)5.77 ± 1.3475.25 ± 1.31˂ 0.05*
LH (mIU/mL)7.37 ± 1.447.12 ± 1.68˂ 0.001*
LH/FSH1.33 ± 0.381.4 ± 0.4570.397
DHEA-S (mg/mL)1.07 ± 0.801.11 ± 0.710.259
Total testosterone (ng/mL)0.82 ± 0.190.71 ± 0.26˂ 0.05*
Androstenedione (ng/mL)1.9 ± 0.501.63 ± 0.580.717
Dietary characteristics
Energy intake (kcal/day)2423.6 ± 329.11409.3 ± 263.3˂ 0.001*
Meal frequency (meals/day)4.6 ± 1.347.08 ± 0.76˂ 0.001*
Proteins (% TCV/day)23.7 ± 6.8437.1 ± 7.8˂ 0.001*
Lipids (% TCV/day)29.5 ± 8.5217.4 ± 4.8˂ 0.001*
CHO (% TCV/day)52.7 ± 15.2240.8 ± 5.49˂ 0.001*
  1. AFC antral follicle cells, FM fat mass, FFM fat-free mass, FMI fat mass index, FFMI fat-free mass index, p HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosteron, TCV total caloric value, *p ˂ 0.05