Skip to main content

Table 1 Clinical, anthropometric, and laboratory characteristics at base line

From: Impact of weight loss on plasma ghrelin level, clinical, and metabolic features of obese women with or without polycystic ovary syndrome

 Control group (mean ± SD), (n = 85)Obese group (mean ± SD), (n = 110)P
Age (years)29.07 ± 6.430.05 ± 6.4730.265
Body mass index (kg/m2)24.55 ± 2.6136.37 ± 2.26˂ 0.001*
Waist/hip ratio0.96 ± 0.1891.24 ± 0.258˂ 0.001*
Systolic blood pressure (mm Hg)127.68 ± 6.54130.95 ± 6.8˂ 0.05*
Diastolic blood pressure (mm Hg)85.18 ± 3.8887.04 ± 4.320˂ 0.05*
Hirsutism score5.42 ± 0.7419.84 ± 4.22˂ 0.001*
Ovarian volume5.15 ± 0.898.783 ± 3.96˂ 0.001*
AFC6.16 ± 1.3199.64 ± 4.21˂ 0.001*
FMI%6.38 ± 0.679.4 ± 0.68˂ 0.001*
FFMI%18.16 ± 1.926.8 ± 1.96˂ 0.001*
Total cholesterol (mg/dL)166.7 ± 20.64198.9 ± 11.18˂ 0.001*
Triglycerides (mg/dL)149.6 ± 11.19260.5 ± 91.46˂ 0.001*
LDL cholesterol (mg/dL)105.8 ± 4.44142.7 ± 13.77˂ 0.001*
HDL cholesterol (mg/dL)51.16 ± 4.3433.8 ± 4.0˂ 0.001*
Fasting blood glucose (mg/dL)85.02 ± 8.9594.01 ± 6.81˂ 0.001*
Fasting serum insulin (lU/mL)6.84 ± 1.44315.1 ± 8.50˂ 0.001*
HbA1c (%)4.77 ± 0.1475.9 ± 0.10˂ 0.001*
HOMA-IR1.43 ± 0.343.53 ± 2.00˂ 0.001*
HOMA β146.5 ± 62.096.8 ± 58.91˂ 0.001*
FSH (mIU/mL)4.89 ± 1.016.06 ± 1.49˂ 0.05*
LH (mIU/mL)6.54 ± 1.227.439 ± 1.5˂ 0.001*
LH/FSH1.52 ± 0.3951.29 ± 0.38˂ 0.001*
DHEA-S (mg/mL)0.92 ± 0.481.45 ± 0.84˂ 0.001*
Total testosterone (ng/mL)0.51 ± 0.150.83 ± 0.23˂ 0.001*
Androstenedione (ng/mL)1.20 ± 0.351.936 ± 0.496˂ 0.001*
Plasma ghrelin (ng/ml)48.21 ± 21.099.49 ± 5.59˂ 0.001*
Dietary characteristics
Energy intake (kcal/day)1813.5 ± 446.642406.8 ± 297.2˂ 0.001*
Meal frequency (meals/day)3.78 ± 1.014.9 ± 1.496˂ 0.001*
Proteins (% TCV/day)21.16 ± 3.00825.21 ± 7.609˂ 0.001*
Lipids (% TCV/day)26.3 ± 3.7431.38 ± 9.469˂ 0.001*
CHO (% TCV/day)47.02 ± 6.6856.04 ± 16.9˂ 0.001*
  1. AFC antral follicle cells, FM fat mass, FFM fat-free mass, FMI fat mass index, FFMI fa-free mass index, p HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosteron, TCV total caloric value*