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Table 1 Clinical, anthropometric, and laboratory characteristics at base line

From: Impact of weight loss on plasma ghrelin level, clinical, and metabolic features of obese women with or without polycystic ovary syndrome

 

Control group (mean ± SD), (n = 85)

Obese group (mean ± SD), (n = 110)

P

Age (years)

29.07 ± 6.4

30.05 ± 6.473

0.265

Body mass index (kg/m2)

24.55 ± 2.61

36.37 ± 2.26

˂ 0.001*

Waist/hip ratio

0.96 ± 0.189

1.24 ± 0.258

˂ 0.001*

Systolic blood pressure (mm Hg)

127.68 ± 6.54

130.95 ± 6.8

˂ 0.05*

Diastolic blood pressure (mm Hg)

85.18 ± 3.88

87.04 ± 4.320

˂ 0.05*

Hirsutism score

5.42 ± 0.741

9.84 ± 4.22

˂ 0.001*

Ovarian volume

5.15 ± 0.89

8.783 ± 3.96

˂ 0.001*

AFC

6.16 ± 1.319

9.64 ± 4.21

˂ 0.001*

FMI%

6.38 ± 0.67

9.4 ± 0.68

˂ 0.001*

FFMI%

18.16 ± 1.9

26.8 ± 1.96

˂ 0.001*

Total cholesterol (mg/dL)

166.7 ± 20.64

198.9 ± 11.18

˂ 0.001*

Triglycerides (mg/dL)

149.6 ± 11.19

260.5 ± 91.46

˂ 0.001*

LDL cholesterol (mg/dL)

105.8 ± 4.44

142.7 ± 13.77

˂ 0.001*

HDL cholesterol (mg/dL)

51.16 ± 4.34

33.8 ± 4.0

˂ 0.001*

Fasting blood glucose (mg/dL)

85.02 ± 8.95

94.01 ± 6.81

˂ 0.001*

Fasting serum insulin (lU/mL)

6.84 ± 1.443

15.1 ± 8.50

˂ 0.001*

HbA1c (%)

4.77 ± 0.147

5.9 ± 0.10

˂ 0.001*

HOMA-IR

1.43 ± 0.34

3.53 ± 2.00

˂ 0.001*

HOMA β

146.5 ± 62.0

96.8 ± 58.91

˂ 0.001*

FSH (mIU/mL)

4.89 ± 1.01

6.06 ± 1.49

˂ 0.05*

LH (mIU/mL)

6.54 ± 1.22

7.439 ± 1.5

˂ 0.001*

LH/FSH

1.52 ± 0.395

1.29 ± 0.38

˂ 0.001*

DHEA-S (mg/mL)

0.92 ± 0.48

1.45 ± 0.84

˂ 0.001*

Total testosterone (ng/mL)

0.51 ± 0.15

0.83 ± 0.23

˂ 0.001*

Androstenedione (ng/mL)

1.20 ± 0.35

1.936 ± 0.496

˂ 0.001*

Plasma ghrelin (ng/ml)

48.21 ± 21.09

9.49 ± 5.59

˂ 0.001*

Dietary characteristics

Energy intake (kcal/day)

1813.5 ± 446.64

2406.8 ± 297.2

˂ 0.001*

Meal frequency (meals/day)

3.78 ± 1.01

4.9 ± 1.496

˂ 0.001*

Proteins (% TCV/day)

21.16 ± 3.008

25.21 ± 7.609

˂ 0.001*

Lipids (% TCV/day)

26.3 ± 3.74

31.38 ± 9.469

˂ 0.001*

CHO (% TCV/day)

47.02 ± 6.68

56.04 ± 16.9

˂ 0.001*

  1. AFC antral follicle cells, FM fat mass, FFM fat-free mass, FMI fat mass index, FFMI fa-free mass index, p HOMA-IR homeostasis model assessments of insulin resistance, DHEA dehydroepiandrosteron, TCV total caloric value*